The generation of human induced pluripotent stem cell lines from individuals of Black African ancestry in South Africa

Jerolen Naidoo, Tracey Hurrell, Janine Scholefield

This research group adresses the inequality in the advancement of health research, due to a lack of equitable representation of African diversity in scientific resources, such as genome-wide association studies and human induced pluripotent stem cell (hiPSC) repositories.

Highlights of this publication:

• hiPSC lines inclusive of African genetic diversity were generated.

• hiPSCs contribute to addressing representation of African genetics in global resources.

• hiPSC lines were successfully differentiated to hepatocyte-like cells.

• hiPSC lines were successfully differentiated into cortical neurons.

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