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The generation of human induced pluripotent stem cell lines from individuals of Black African ancestry in South Africa

Writer's picture: Lize EngelbrechtLize Engelbrecht

Jerolen Naidoo, Tracey Hurrell, Janine Scholefield


This research group adresses the inequality in the advancement of health research, due to a lack of equitable representation of African diversity in scientific resources, such as genome-wide association studies and human induced pluripotent stem cell (hiPSC) repositories.


Highlights of this publication:

  • hiPSC lines inclusive of African genetic diversity were generated.

  • hiPSCs contribute to addressing representation of African genetics in global resources.

  • hiPSC lines were successfully differentiated to hepatocyte-like cells.

  • hiPSC lines were successfully differentiated into cortical neurons.




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